Sunday, January 1, 2012

Your Insides Out: The History of Visualization of Biological Macromolecules On-line Museum

Look at the title above.  Does it make any sense to you?  Probably not, unless you've got some college-level biology classes under your belt.  I had to read the opening page of this museum - and then re-read it to make sure I caught all the salient points, and then look at some of the images - before I understood what this museum is about.  This is kind of how the museum operates:  slightly confusing for the layman but full of pretty pictures.

Biological macromolecules are the larger molecules in our bodies, like proteins and the nucleic acids in our DNA.  Collected here are images and movies scientists in earlier generations produced in order to bring these macromolecules to a human scale.  The earliest images come from 1946 and were created in MIT laboratories.  There is also a 3D model of a protein, some pictures of crystals, and the cover of a 1966 molecule catalog (unfortunately, the link to flip through the catalog is no longer working).

The coolest section is the Early Molecular Graphics Movie Gallery, which shows films of protein and insulin molecules from 1966 and 1971.  They're on the primitive side, but it's interesting to see just what these structures look like.

Each section is accompanied by plenty of footnoted text, but it's not too user-friendly.  I suspect this was written with fellow scientists, not the general public, in mind.  That makes this museum frustrating, because with a more explanatory tone these images could provide a truly enlightening look inside our bodies.

So stop by and take a look, and try to glean what you can, but don't feel bad if it doesn't make sense to you.


History of Visualization of Biological Macromolecules On-line Museum
Mission:  This site is an on-line archive dedicated to the various tools and techniques that have been used by molecular scientists to visualize and study the structure of biological macromolecules.
Website:  www.umass.edu/molvis/francoeur/index.html

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